Core Balance
clearer skin, and I started losing weight." — Mia L.
For optimal results, we recommend 10 to 16 weeks of consistent daily use. Most clinical research on inositol runs this long — your body needs time to respond.
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clearer skin, and I started losing weight." — Mia L.
clearer skin, and I started losing weight." — Mia L.
Core Balance
The Science Behind Core Balance
Myo-inositol is the primary form of inositol studied for PCOS. It supports insulin signaling pathways and ovarian function.
Why this amount: Clinical studies on ovulatory function use 4,000mg daily. Most supplements give you 500-2,000mg. We give you the full research-backed amount, split AM/PM for steady levels.
Berberine is a plant compound studied for its effects on glucose metabolism and insulin sensitivity. It works through similar pathways as some pharmaceuticals—which is why you should talk to your doctor if you're on Metformin.
Why this amount: Research on berberine uses 1,000-1,500mg daily. We included 1,000mg, split across AM/PM to support steady metabolic function throughout the day.
Alpha-lipoic acid (ALA) is an antioxidant that supports cellular energy metabolism and has been studied alongside inositol for metabolic support in women with PCOS.
Why this amount: Studies examining ALA for metabolic support typically use 200-600mg. We included 200mg in the AM formula to complement the inositol foundation without overcomplicating the stack.
Vitamin D deficiency is common in women with PCOS and associated with metabolic and hormonal markers. Supplementation supports overall hormonal function and immune health.
Why this amount: Many women with PCOS have suboptimal vitamin D levels. 4,000 IU is a meaningful amount for most adults, though your provider may recommend more based on your bloodwork.
Chromium picolinate is a trace mineral that plays a role in insulin signaling and glucose metabolism. It's one of the most-studied minerals for supporting healthy blood sugar already within normal range.
Why this amount: Research on chromium for metabolic support typically uses 200-1,000µg. We included 200µg as a foundational amount that complements the berberine and inositol.
L-cysteine is an amino acid precursor to glutathione, your body's master antioxidant. It also provides sulfur for keratin production, supporting healthy hair—a common concern for women with PCOS.
Why in PM: Antioxidant and cellular repair processes are more active during sleep. L-cysteine in the evening supports overnight recovery.
D-chiro-inositol works alongside myo-inositol. The ratio between them matters: healthy ovarian tissue naturally maintains approximately a 40:1 myo to D-chiro ratio. Too much D-chiro can actually be counterproductive.
Why this amount: 100mg D-chiro with 4,000mg myo-inositol = the 40:1 ratio. This isn't a marketing number. It's based on what research shows about optimal inositol balance.
What to expect (realistically)
Week 1-2
You probably won't notice much. That's normal. Your body is building consistent levels of these nutrients.
Week 3-4
Some women notice subtle shifts—energy, cravings, how they feel before their period. Others don't yet.
Month 2-3
This is when most women see changes in cycle regularity. If you track your cycle, you may notice more predictable patterns.
Month 3-4+
Continued support. Most clinical studies on inositol run 3-6 months. Consistency matters more than perfection.
Everyone responds differently. If you're not seeing changes by month 3, it's worth checking in with your healthcare provider about your overall protocol.
Build On Your Foundation
We love questions
One box is a 30-day supply when used as directed (4 capsules AM, 4 capsules PM). Subscribe for 3 or 6 months for the best value and to stay consistent through the full benefit window.
Because therapeutic amounts require volume. 4,000mg of myo-inositol plus 1,000mg of berberine plus supporting nutrients won't fit in 2 capsules. We chose efficacy over convenience—and splitting AM/PM improves absorption.
Berberine works through similar mechanisms as Metformin. If you're currently taking Metformin, consult your healthcare provider before adding Core Balance. Bring this ingredient list to your appointment.
Take it when you remember. If it's close to your next serving, skip the missed one—don't double up. Consistency over time matters more than perfection on any single day.
Many women take inositol while trying to conceive—it's been studied in this context. However, if you're actively trying to conceive or undergoing fertility treatment, please consult your healthcare provider before starting any new supplement.
Subscribe & Save gets you up to 30% off. Your order ships automatically on your schedule (every 1, 3, or 6 months). Edit, skip, or cancel anytime from your account—no commitment, no hassle.
How to take Core Balance
Morning — AM Formula
Take 4 capsules with breakfast and water.
Delivers: Myo-inositol, D-chiro-inositol, berberine, alpha-lipoic acid, vitamin D₃, chromium
Evening — PM Formula
Take 4 capsules with dinner and water.
Delivers: Myo-inositol, D-chiro-inositol, berberine, L-cysteine, chromium
That's it. 8 capsules daily, split between meals for better absorption.