Core Balance
clearer skin, and I started losing weight." — Mia L.
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clearer skin, and I started losing weight." — Mia L.
clearer skin, and I started losing weight." — Mia L.
Core Balance
Don't Just Take Our Word.
I can literally write an essay about the effects of these pills but I'm just going to say that they changed my life over a summer..
I'd tried cheap inositol off Amazon and felt nothing. The full dose here and the AM/PM thing is the first time I actually noticed a change.
Month one I almost quit, nothing. Glad I didn't. By month three my cycle showed up on its own for the first time in a year.
I'm on my second bottle and the dark hairs on my chin are coming in finer and slower. I've waxed for ten years. Took me long but nothing else touched the actual problem.
Came for the facial hair (still slowly working on that). but my afternoon energy crash kind of... stopped? didn't connect those were related.
Everything I'd tried treated one symptom at a time. This is the first thing that went after whatever was actually causing all of them.
Results shown are individual experiences. Results may vary.
The Science Behind Core Balance
Myo-inositol is the primary form of inositol studied for PCOS. It supports insulin signaling pathways and ovarian function.
Why this amount: Clinical studies on ovulatory function use 4,000mg daily. Most supplements give you 500-2,000mg. We give you the full research-backed amount, split AM/PM for steady levels.
Berberine is a plant compound studied for its effects on glucose metabolism and insulin sensitivity. It works through similar pathways as some pharmaceuticals—which is why you should talk to your doctor if you're on Metformin.
Why this amount: Research on berberine uses 1,000-1,500mg daily. We included 1,000mg, split across AM/PM to support steady metabolic function throughout the day.
Alpha-lipoic acid (ALA) is an antioxidant that supports cellular energy metabolism and has been studied alongside inositol for metabolic support in women with PCOS.
Why this amount: Studies examining ALA for metabolic support typically use 200-600mg. We included 200mg in the AM formula to complement the inositol foundation without overcomplicating the stack.
Vitamin D deficiency is common in women with PCOS and associated with metabolic and hormonal markers. Supplementation supports overall hormonal function and immune health.
Why this amount: Many women with PCOS have suboptimal vitamin D levels. 4,000 IU is a meaningful amount for most adults, though your provider may recommend more based on your bloodwork.
Chromium picolinate is a trace mineral that plays a role in insulin signaling and glucose metabolism. It's one of the most-studied minerals for supporting healthy blood sugar already within normal range.
Why this amount: Research on chromium for metabolic support typically uses 200-1,000µg. We included 200µg as a foundational amount that complements the berberine and inositol.
L-cysteine is an amino acid precursor to glutathione, your body's master antioxidant. It also provides sulfur for keratin production, supporting healthy hair—a common concern for women with PCOS.
Why in PM: Antioxidant and cellular repair processes are more active during sleep. L-cysteine in the evening supports overnight recovery.
D-chiro-inositol works alongside myo-inositol. The ratio between them matters: healthy ovarian tissue naturally maintains approximately a 40:1 myo to D-chiro ratio. Too much D-chiro can actually be counterproductive.
Why this amount: 100mg D-chiro with 4,000mg myo-inositol = the 40:1 ratio. This isn't a marketing number. It's based on what research shows about optimal inositol balance.
What to expect (realistically)
Week 1-2
You probably won't notice much. That's normal. Your body is building consistent levels of these nutrients.
Week 3-4
Some women notice subtle shifts—energy, cravings, how they feel before their period. Others don't yet.
Month 2-3
Where most women see change - more predictable cycles, and the first real shifts in skin and unwanted hair.
Month 3-4+
This is where root-cause work settles in. Consistency beats perfection. It's also where the hair changes take hold.
Everyone responds differently. If you're not seeing changes by month 3, it's worth checking in with your healthcare provider about your overall protocol.
Build On Your Foundation
We love questions
One box = two jars = a 30-day supply.AM: 4 capsules with breakfast (inositols, berberine, ALA, vitamin D3, chromium). PM: 4 capsules with dinner (inositols, berberine, L-cysteine, chromium). Always with food and a glass of water.
Everything is on the label at its real amount — no proprietary blends. Daily: 4,000mg myo-inositol with D-chiro-inositol at 40:1, 1,000mg berberine, 200mg ALA, 300mg L-cysteine, 200µg chromium, 4,000 IU vitamin D3. Made in a cGMP, FDA-registered facility and third-party tested for purity and potency.
This one's a real question for your prescriber. Berberine can interact with some medications, and it also supports blood sugar — which matters if you're on metformin or anything else glucose-related. Every ingredient and amount is on the label, so take it (or this page) to your doctor or pharmacist; it's a short conversation.
Please wait. Some ingredients — berberine in particular — aren't recommended during pregnancy. If you're trying to conceive, talk to your provider first. This is one of the "not right now" cases we flag on purpose.
Most women tolerate it well. The most common adjustment is mild digestive grumbling in the first days (usually the berberine) — taking it with food as directed handles most of it. If anything feels off, pause and check with your provider.
No. Subscribe & Save takes 10–30% off and you can skip, pause, or cancel anytime from your account — no minimums, no cancellation fees. Prefer not to subscribe? Buy Once is right there. (If you're planning to give it the full 90 days anyway, the 3-pack is simply saves you more while doing the same thing.)
Orders placed before 11 AM ship the same day. Shipping is free on orders over $75 — so every Core Balance order ships free.